Washington University in St. Louis

Triple Drug Therapy for LF

Comparison of safety profile and acceptability between triple drug therapy (IVM,DEC,ALB) and standard two-drug therapy (DEC, ALB), plus STH evaluation.

A comparison study of ICT cards and the new Filariasis Test Strip (FTS)

Comparison of ICT and FST.

Study Findings:

  • A total of 2,956 samples were investigated simultaneously via ICT cards and FTS - representative of the population of six health districts that had conducted five rounds of MDA for lymphatic filariasis.

  • The multi-country studies on the same topic led to the endorsement by WHO for the FTS as an approved diagnostic tool.
Countries: Niger | Liberia

Integrated Remapping of lymphatic filariasis and loiasis (Cameroon)

Defining what are the appropriate tools to map LF in Loa endemic areas. Identifying if there is a Loa infection threshold that triggers the cross-reactivity in the ICT cards.

Countries: Cameroon

Analysis of MDA frequency and Brugia in Indonesia

Comparison of 2X vs. 1X per year MDA on Brugia with MDA of DEC/Alb , plus STH evaluation

Countries: Indonesia

Comparison of Filariasis Binax Test and Alere Test Strip

Binax Now Filariasis Test vs. Alere Filariasis Test Strip Comparison

Countries: Liberia | Indonesia | Sri Lanka

Analysis of MDA frequency in Liberia and Cote D'Ivoire

Comparison of 2X vs. 1X per year MDA on W. bancrofti with MDA of IVM/Alb, plus STH evaluation (and Schistosoma in Foya only)

Countries: Liberia | Cote d'Ivoire

Analysis of MDA frequency in Indonesia and Papua New Guinea

Comparison of 2X vs. 1X per year MDA, W. bancrofti with MDA of DEC/Alb, plus STH evaluation