Evaluation of community directed vector control on transmission of Onchocerca volvulus in a Loa loa co-endemic region
This study will pilot the Slash and Clear methodology in an oncho-Loa loa co-endemic setting. Previous pilots in Uganda and Nigeria have demonstrated that this simple strategy of removing breeding sites can result in significant black fly reductions that last for several months. This study will provide important data on the impact of Slash and Clear on black fly biting, and consequently its impact on oncho elimination. Two intervention and one control community will be compared for two years, with repeated measurements being taken of biting rates.
Our proposal will study the interaction between humans, livestock and wildlife and the role of this transition zone in the transmission of trypanosomes at the edge of the Serengeti National Park in Tanzania. To assess whether focussed control of tsetse is effective, we will develop mathematical models of the transmission of trypanosomes in the transition zone from wildlife-dominated areas on the park boundaries through to livestock-dominated areas outside the parks. The models will enable us to predict the likely extent, duration and cost of interventions required to interrupt the transmission of trypanosomes at boundary areas.
Understanding how mosquitoes survive a blood meal
Explore the use of tiny targets to control Human African Trypanosomiasis (HAT) in Chad
To determine the effectiveness of tiny target technology in controlling tsetse vectors for Human African Trypanomiasis
Molecular tools for insecticide resistance diagnosis in phlebotomine sandflies for sustainable leishmaniasis control and elimination programme
Developing new diagnostic tools to monitor insecticide resistance in sandflies in India
Improving the impact of IRS for Visceral Leishmaniasis with enabling integrated decision support systems
Improving effectiveness of vector control against Visceral Leishmaniasis
Defining the insecticide resistance status of dengue vectors in Jeddah and Makkah; essential prerequisite to developing an effective response in the event of an outbreak in these important sites.
Assessing treatment needs for school-aged children and assisting Ministry of Health to develop an effective control programme
Understanding the basic pharmacology of praziquantel tailored to paediatric setting and developing a treatment access plan for this age class