Schistosomiasis

Alternative approaches to coverage surveys (Uganda)

To compare coverage evaluation methods to identify a method that is statistically rigorous and feasible for programs. This study will focus on assessing MDA coverage for lymphatic filariasis by comparing the cost, time and feasibility of 3 different methods: the EPI approach (n=1768), LQAS design (n=95) and probability sampling alternatives (n=1768).

Primary Findings and Lessons Learned

Coverage surveys are an important tool for programs to evaluate their reporting systems and to determine whether effective MDA coverage has been achieved. However, for various reasons coverage surveys are seldom implemented.  Some key challenges are: perceived technical difficulty, lack of resources, and lack of standardized guidance on how to conduct coverage surveys.  This protocol seeks to address the 1st and 3rd points by comparing the feasibility of three different coverage survey methods (EPI approach, LQAS, and segmentation).     This study was completed in 3 districts in Burkina Faso.  All 3 districts found that their survey coverage was above the WHO target threshold (65% for LF).  Furthermore, in all 3 cases the survey coverage validated (or nearly validated) the reported coverage. Taken together this suggests that the Burkina Faso program is working well.   The feasibility results found all 3 methods to be very similar with regards to time, cost and perceived difficulty.  Because only the segmentation approach results in a probability sample, this method was recommended by the M&E Working Group and ultimately approved by the STAG.  Since the approval, significant work has been underway to create guidelines for conducting coverage surveys for preventive chemotherapy.  An excel tool was created to improve the usability of the tool and online learning modules are currently in the works.

Countries: Uganda

Evaluation of CCA urine-tests for diagnosis of Schistosoma guineensis infection in Cameroon

To determine if the circulating cathodic antigen (CCA) rapid diagnostic test is as effective as the Kato-Katz (KK) test in diagnosing S. guinensis

Countries: Cameroon
Diseases: Schistosomiasis

Rapid Answer Projects (RAPs)

Literature review, meta-analyses; 3 RAPs published; one RAP white paper; see SCORE website http://score.uga.edu/projects/rapid-answers-project/

Countries:
Diseases: Schistosomiasis

Riverine Prawns

What is the the impact of riverine prawns on infections in humans? Studies are to be conducted on interrupting seasonal transmission of Schistosomiasis and ecologic assessment of riverine prawns on infections in humans.

Countries: Cote d'Ivoire
Diseases: Schistosomiasis

Elimination of S. haematobium in Seasonal Transmission Sites

This study will include comparing 1) MDA as usual 2) double treatment with two closely-spaced MDAs (consistent with the recommendation based on mathematical models) 3) twice yearly MDA and 4) double MDA plus snail control.

Countries: Cote d'Ivoire
Diseases: Schistosomiasis

Field evaluation of two schistosome antibody-based rapid tests at point-of-care for prevalence mapping of urinary schistosomiasis in The Gambia

CCA Protocol: To know the sensitivity and specificity of POC CCA in the detection of urinary schistosomiasis, as compared to traditional diagnostic tools.

Countries: Gambia
Diseases: Schistosomiasis

Multi-country perspective on mobile data collection

SCORE Data Collection on Mobile Devises

Diseases: Schistosomiasis

Snail control in Kenya with 20 year follow-up

Snail Control follow-up study of P. clarkii 20 years later

Countries: Kenya
Diseases: Schistosomiasis

Analysis of schistosomiasis diagnostics

Human Diagnostics Tool Development (CAA diagnostic tool)

Countries: Tanzania
Diseases: Schistosomiasis

Cross-country analysis of CCA test for screening/mapping

POC/CCA screening/mapping tool initial Studies

Diseases: Schistosomiasis

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