Other research topic

Achieving LF Elimination in the Pacific Island Countries

Organize existing data for preparation of LF elimination dossiers based on the PacELF programs.

Countries: Japan | Australia

Defining the Profile of LF Antibody Reactivity following MDA

Determine age-specific prevalence of LF Antibody following MDA to inform surveillance strategies.

Countries: French Polynesia

mHealth Platforms - Operational Research to optimize approaches to improve data flow and accounting

Determine the best data-capture system and implementation model to overcome data flow challenges faced by national MDA programs. Test and compare the effectiveness of 4 different data-tracking platforms currently in use (or development) in NTD endemic countries: 1) Build on existing national capacity, 2) Cloud-based SMS system, 3) Robo-call platform.

Preliminary study findings:

o The current process for tracking treatment information through paper-based forms can be complicated and leaves room for human error, as multiple aggregations of data must be collected manually between administrative levels before reaching the national level. 

o This study found that the process of collecting and reporting paper records on the stock and delivery of ivermectin, albendazole and Praziquantel took between two and three months. 

o The study found that robo-call surveys have the potential to add a new stream of information on drug stock between national supervisors and sub-district implementation teams, allowing program staff to take corrective actions in response to issues with drug supply.

o The proactive timing of the calls as well as the interactive component of responding to verbal questions through the phone makes this system useful to supervisors. 

o Robo-calls were found to be helpful to monitor drug levels prior to MDA at sub-district level and to ensure appropriate quantities of drug stock were reaching lower administrative level, but as post-MDA drug stock is returned to the district level, physical observation of district-level storerooms was the most effective way to assess drug quantities post-MDA.  

o SMS reporting made data accessible at the national level and to administrative units in real time. 

o Less than half of the registered supervisors submitted SMS reports, resulting in a significant difference in the number and type of treatments reported when compared to paper forms. 

o Greater training and ongoing management is needed to take full advantage of the speed and data accuracy improvements from robo-call and SMS surveys.

 

Countries: Uganda

Rapid Answer Projects (RAPs)

Literature review, meta-analyses; 3 RAPs published; one RAP white paper; see SCORE website http://score.uga.edu/projects/rapid-answers-project/

Countries:
Diseases: Schistosomiasis

Randomized Control Trial Comparing Efficacy of a Single Dose of Treatment of Yaws with 20 mg/kg Versus 30 mg/kg of Azithromycin

Non-inferiority study comparing a 20mg/kg dosing strategy of azithromycin to a 30mg/kg dosing strategy in the treatment of yaws 

Countries: Papua New Guinea | Ghana
Diseases: Yaws

Modeling

Define improved strategies, support development of WHO recommendations, and ensure communication to struggling countries; Acceleration of global elimination efforts to achieve 2020 goals

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