Loiasis

Comparison of FTS antigen and Wb123 ELISA in a co-endemic LF and Loiasis area (Or Integrated lymphatic filariasis and Loiasis mapping)

Compare lymphatic filariasis FTS antigen prevalence to the Wb123 antibody prevalence in an area co-endemic with Loa-loa. Refine LF prevalence with FTS and provide evidence for MDA intervention by excluding areas where prevalence of ICT card is due to Loa loa cross reaction; 2) Provide additional data to address the influence of Loa loa cross-reaction and the specificity of antigen rapid test positive result alone to identify ongoing LF transmission in areas co-endemic for LF and Loiasis.

Evaluation of LF diagnostic Tools in Loa-Endemic Areas

To assess the specificity of diagnostic tools in Loa co-endemic areas and to conduct a prospective assessment of the impact of ALB MDA and Vector control on malaria, LF and STH indicators.

Countries: Cameroon

Multi-country comparison of diagnostics tools for Onchocerca volvulus, Wuchereria bancrofti and Loa loa

Comparison of different diagnostic tools during onchocerciasis, lymphatic filariasis and Loa loa mapping and epidemiological assessments, including Ov16 ELISA, OV16 rapid diagnostic test (RDT) and skin snip test. (Refer to 065.1, 065.2, 065.3, 65.6 & 65.7.)

Countries:

Correlating Ov16 Serology with Skin Snip Assessments (Gabon)

Comparison of different diagnostic tools during onchocerciasis mapping, including Ov16 ELISA, OV16 rapid diagnostic test (RDT) and skin snip test.

Countries: Gabon

Correlating Ov16 Serology with Skin Snip Assessments (DRC)

To compare different diagnostic tools during onchocerciasis mapping, including Ov16 ELISA, OV16 rapid diagnostic test (RDT) and skin snip test.

Countries: Dem. Rep. of Congo

Integrated Remapping of lymphatic filariasis and loiasis (Cameroon)

Defining what are the appropriate tools to map LF in Loa endemic areas. Identifying if there is a Loa infection threshold that triggers the cross-reactivity in the ICT cards.

Countries: Cameroon

Analysis of MDA for LF in loa endemic countries

Community MDA with 2X Alb alone for W. bancrofti in areas co-endemic for L. loa, plus STH evaluation

Countries: Congo | Dem. Rep. of Congo

Comparison of Filariasis Binax Test and Alere Test Strip

Binax Now Filariasis Test vs. Alere Filariasis Test Strip Comparison

Countries: Liberia | Indonesia | Sri Lanka

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