Human African trypanosomiasis (sleeping sickness)

Our proposal will study the interaction between humans, livestock and wildlife and the role of this transition zone in the transmission of trypanosomes at the edge of the Serengeti National Park in Tanzania. To assess whether focussed control of tsetse is effective, we will develop mathematical models of the transmission of trypanosomes in the transition zone from wildlife-dominated areas on the park boundaries through to livestock-dominated areas outside the parks. The models will enable us to predict the likely extent, duration and cost of interventions required to interrupt the transmission of trypanosomes at boundary areas. 

Explore the use of tiny targets to control Human African Trypanosomiasis (HAT) in Chad

Determine the effectiveness of integrated control of Human African Trypanosomiasis (HAT) in a model district in DRC

To determine the effectiveness of tiny target technology in controlling tsetse vectors for Human African Trypanomiasis

Which strategies best strengthen strategic decision making for resilient and responsive health systems at the district level in Ghana, Malawi, Uganda and Tanzania?

How to best support close-to-community providers in their critical interface role between health systems and communities

What are the best approaches to develop sustainable and equitable approaches to human resources for health, health financing and governance in post conflict health systems?

What are the most strategic approaches to building capacity for gender equity analysis in health systems?

Determine the best health systems approaches for:

1. Improved planning and delivery of integrated programmes; 
2. Increased and sustained access to NTD drugs; 
3. Harmonised inter-sectoral approach; and 
4. Strong and generalisable evidence base for integrated elimination and control of NTDs.

Assessing treatment needs for school-aged children and assisting Ministry of Health to develop an effective control programme