UK aid

Field testing the use of 3D photographs of trachomatous trichiasis to train trachoma field graders

To evaluate 3D photographs of trachomatous trichiasis (TT) in the training and assessment of trachoma graders.

Countries: Ethiopia
Diseases: Trachoma

Long term outcome of the two most commonly used surgical procedures to treat trachomatous trichiasis (TT): PLTR vs BLTR

Ascertain whether the difference in outcome (measured in rate of post-operative trachomatous trichiasis, or TT), between the posterior lamellar tarsal rotation (PLTR) and bilamellar tarsal rotation (BLTR) is sustained at four years or whether they give different results from what has been found at 1 year.

Countries: Ethiopia
Diseases: Trachoma

Antibody Responses to Chlamydia trachomatis Antigens in Trachoma-Endemic Zones of Ethiopia

To analyze the relationships between the currently used indicator for impact assessments - prevalence of the clincial sign TF - and the prevalence of infection and antibody among 1-9 year old children in hyperendemic districts prior to mass drug administration

Countries: Ethiopia
Diseases: Trachoma

Determining end markers for stopping MDA for Trachoma in Malawi

Currently MDA is stopped when TF in children aged 1-9 years is below 5%. However, the relationship between TF, presence of infection and antibody has not been studied in a sufficient number of settings to enable predictions of outcome to be confidently made based on baseline prevalence, intervention coverage, and the prevalence of disease and infection at the time of impact survey. There are several districts in Malawi with TF prevalence between 5 and 9.9% which are eligible for one year of interventions, including a single round of MDA. This study will add important data to be used to model outcomes of interventions conducted by trachoma elimination programs, and in particular, help develop operational guidelines for stopping MDA.

Countries: Malawi
Diseases: Trachoma

Estimating Population Denominators and Coverage of Mass Drug Administration Using Polio’s Vaccination Tracking System

To determine the viability of utilizing the polio program’s Vaccination Tracking System (VTS) to generate more accurate population, drug requirement and coverage estimates in NTD programs

Countries: Nigeria
Diseases: Trachoma

The Impact of an Enhanced Antibiotic Treatment Regimen on Trachoma in Amhara, Ethiopia

What are the differences at 1 year post-baseline in the prevalence of trachoma and Ct infection in villages randomized to an enhanced antibiotic treatment regimen characterized by a routine community-wide MDA followed by two rounds of treatment targeted to children 6 months to 9 years in quick succession (1-2 weeks apart) compared to villages randomized to annual standard-of-care community-wide MDA?

Countries: Ethiopia
Diseases: Trachoma

COUNTDOWN Calling

Helping increase and sustain the scale-up of preventive chemotherapy campaigns in West and Central Africa

Countries:

Strengthen the capacity of the 5 African university departments hosting the MCDC programme

To strengthen the capacity of the 5 African university departments hosting the Malaria Capacity Development Consortium (MCDC) programme

Countries: Senegal | Mali | Gambia | | Ghana

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