United Kingdom of Great Britain and Northern Ireland

Country operational research priorities pending.

Studies

Can geostatistical tools be used to develop a stop IDA strategy for LF that can measure <1% Mf prevalence in adults?

Districts: NA

The purpose of this project is to create maps that utilize LF risk and prevalence data to predict risk of recrudescence, and to stratify this risk into 3-4 distinct groups. Such maps could subsequently be used to design and simulate the performance of different surveillance strategies. 

Preliminary study findings:

  • The intensity of transmission was quantified by the basic reproductive number (R0).

  • A map of predicted prevalence of microfilaraemia, developed through Bayesian geostatistical modelling, was linked to mathematical models of the transmission dynamics of lymphatic filariasis.

  • The models predict a marked geographical heterogeneity in the intensity of lymphatic filariasis transmission in Sub-Saharan Africa.

  • Further control efforts may be required in areas of higher intensity of transmission.

  • Conversely, interruption of transmission might be achieved earlier in areas of low intensity of transmission.

  • The results suggest that intensity of transmission at baseline (R0) and bednet use are the best indicators for the level of surveillance required sub-nationally post-MDA.

Districts:

Define improved strategies, support development of WHO recommendations, and ensure communication to struggling countries; Acceleration of global elimination efforts to achieve 2020 goals

Districts: