Tools and resources
The new World Health Organization (WHO) guidelines for stopping mass drug administration (MDA) and verification of elimination of human onchocerciasis require evaluating children under the age of 10 years using a serologic test for the detection of IgG4 antibody to the Ov-16 antigen. The designated sampling frame is designed to provide a 95% confidence interval (CI) that excludes 0.1%, and it assumes that the test is 100% sensitive and 100% specific.
The 2016 annual meeting of the Coalition for Operational Research on Neglected Tropical Diseases (COR-NTD) was held November 10 & 11, 2016, in Atlanta, Georgia. This table captures the key knowledge gaps and recommended next steps identified by the leaders of the 18 breakout sessions held at that event.
The target audience for these guidelines is district-level implementation agencies that are concerned with achieving their targets for mass drug administration. The purpose of these guidelines is to introduce the following.
• The concept of narratives and how they can be a valuable tool in understanding people’s health behaviors in the context of NTD control and elimination as well as in other programs;
This page describes a call for proposals which has since closed. Please refer back to this page for updates.
The Supervisor's Coverage Tool (SCT) is a rapid in-process monitoring tool designed to improve coverage during the current round of mass drug administration within a given supervisory area. The SCT has also been shown to be a useful supervisory tool for first-level supervisors and community drug distributors.
The Onchocerciasis IgG4 test is a rapid diagnostic test that qualitatively detects IgG4 antibodies against the Ov16 antigen in human blood samples. This guide will demonstrate how to use and interpret the test. Although the test is relatively simple to use, adequate training is necessary to reduce inter-observer variability and interpretation error.
This is a modifiable example of a paper-based questionnaire for conducting Post-MDA Coverage Surveys.
Partners in the national, international, academic, industrial and philanthropic sectors work together to develop new technologies in the fight to control and eliminate neglected tropical diseases. Click on the links to the right to view infographics on the Alere Filaraisis Test Strip, the Ov16 Rapid Diagnostic Test, the Wb123 Rapid Diagnostic Test, the Ov16/Wb123 Biplex and the Pgp3 Lateral Flow Assay. Team members are listed in alphabetical order.
The Brugia Rapid test has been shown to be a useful and sensitive tool for the detection of Brugia malayi and Brugia timori antibodies and is being used widely by lymphatic filariasis elimination programs in Brugia spp. endemic areas. Although the test is relatively simple to use, adequate training is necessary to reduce inter-observer variability and to reduce the misreading of cassettes.