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WHO Issues Fourth Report on Neglected Tropical Diseases & Other NTD News

News roundup

This news roundup is a collection of headlines and other items on neglected tropical diseases, and does not reflect the work or the views of the Neglected Tropical Diseases Support Center. 

WHO 4th Report on NTDsThe proportion of implementation units delivering preventive chemotherapy and achieving effective coverage shows a significant increase for four of the five diseases amenable to preventive treatment.

WORLD HEALTH ORGANIZATION

 

Lymphatic filariasis

Bill Gates Enthusiastic about Disease-Fighting Progress

Christine Gorman
Scientific American
Looking ahead, some of the most exciting news is likely to come in the treatment of lymphatic filariasis...No one knows why the three-drug combination is better than the standard two-drug treatment. But the three-drug approach has since been fast-tracked for approval, assuming a large-scale efficacy test of 10,000 people confirms positive results at the end of May. Health experts are cautiously optimistic. “We know that we haven’t had any serious adverse events from the combination," says Julie Jacobson, a senior program officer at the Gates Foundation. “If this works, the gain will be huge.”

The role of 'omics' in the quest to eliminate human filariasis

Sara Lustigman, Alexandra Grote and Elodie Ghedin
PLoS Neglected Tropical Diseases
Although there has been much progress in the research and control of human filariasis, major obstacles remain that challenge the global public health community and for which fundamental and applied research is urgently needed. Genomes of filarial parasites are becoming increasingly available and through the related advances in transcriptomics and proteomics promise to revolutionize the field of helminth filarial biology and help unravel new targets for control and novel diagnostic tools. Without accurate annotation and the development of novel functional genomic tools, these data will not be truly valuable to support the better understanding of the filarial biology, host-parasite interactions and symbiosis.

Onchocerciasis

Merck Donates $300,000 to Support Neglected Tropical Disease Elimination Efforts in Africa

Claire Gillespie, Jeanine Clemente, Joni Lawrence and Yao Sodahlon
Business Wire
Merck, known as MSD outside the United States and Canada, announced today a $300,000 cash donation to support non-governmental organization (NGO) partners working to eliminate river blindness (onchocerciasis) and lymphatic filariasis (LF) in Africa. The donation will be offered to 10 NGOs beginning this year, and will be administered through the MECTIZAN® Donation Program (MDP), a public/private partnership established in 1987 following the announcement by Merck to donate MECTIZAN® to control and eliminate river blindness.

The Path to the Elimination of Onchocerciasis in the Americas

Centers for Disease Control and Prevention
Under the guidance of [the Onchocerciasis Elimination Program for the Americas, or] OEPA—and through the coordinated efforts of the Ministries of Health, the Mectizan Donation Program, The Carter Center, CDC, the Lions Club International, and PAHO—elimination of onchocerciasis in the Americas can be achieved by 2022. Success of the elimination program in the Americas thus far has allowed us to move the goal from control of river blindness to full interruption of disease transmission, and ultimately to the global elimination of this disabling parasitic disease.

Potential Cause of Nodding Syndrome Identified

M.J. Friedrich
Journal of the American Medical Association
Nodding syndrome, a rare form of epilepsy that has affected thousands of children between the ages of 5 and 15 years in East Africa, may be caused by an inappropriate immune reaction to the parasitic worm, Onchocerca volvulus, that causes onchocerciasis (river blindness), according to a report published in Science Translational Medicine. First documented in Tanzania in the 1960s, nodding syndrome has remained an untreatable disease characterized by seizures, neurological deterioration, and a high rate of death. Although the cause of nodding syndrome has been elusive, an increase in the condition in areas where the parasite O volvulus is endemic suggests that infection with the worm plays a role in disease pathogenesis.

Schistosomiasis

The evolving schistosomiasis agenda 2007-2017—Why we are moving beyond morbidity control toward elimination of transmission

Charles H. King
PLoS Neglected Tropical Diseases
For the next decade, these should be some of the objectives on our to-do list: Broader and continued implementation of preventive chemotherapy MDA at > 75% coverage; Completion of Phase III trials and licensing of a pediatric formulation for praziquantel; Better coordination and interfacing of the schistosomiasis control community with programs focused on early childhood development, maternal health, and advanced schistosomiasis patient management; Morbidity outcome studies using our new, more sensitive diagnostics, specifically to accurately quantify and better understand the impacts of early childhood schistosomiasis and of genital schistosomiasis; Continued new drug and vaccine development; and Complex intervention trials (at a sufficiently large scale) on the elimination of Schistosoma transmission using combined drug, snail control, behavior change, and WaSH interventions.

Newsday: Interview with Johannes Waltz, Global Schistosomiasis Alliance

BBC
Now, we all know about malaria - huge killer, biggest tropical disease - but what's at number 2? The fact that many of us can't perhaps even pronounce it easily gives an example of a forgotten disease, a disease of poverty...So, what is that second-most widespread tropical disease? Schistosomiasis, or bilharzia, caused by a parasitic worm carried by a freshwater snail, kills over 200,000 people a year. It ruins many, many more lives. [Segment begins at 47:56.]

Enlisting Women in Africa’s Health Fight

Matshidiso Moeti
Project Syndicate
Neglected Tropical Diseases (NTDs) disproportionately affect women and girls. Female genital schistosomiasis (FGS) alone causes severe pain, bleeding, and lesions in more than 16 million women and girls in Sub-Saharan Africa...Because women and girls in their childbearing years suffer disproportionately from the health and social effects of NTDs, it is critically important that they be included in any large-scale health-policy interventions that are proposed. And, beyond making women the focus of NTD programs, we should acknowledge that they will play a central role in advancing the sustainable development agenda.

Ministry of Health to conduct survey to determine prevalence of Snail Fever in communities

St. Lucia Times
“This is a very important survey that will confirm that we no longer have schistosomiasis, and most importantly, to find out if there has been any recent transmission, identify the areas where there is transmission, and to move quickly to eliminate it,” Nahum Jn. Baptiste, National Epidemiologist in the Ministry of Health said. “We’ve had communities in Saint Lucia that have had [transmission rates] as high as 60 percent in the past. We know that we eliminated that disease way back in 1985, but over the last 10 years we have seen about 37 cases, and among them, one school aged child. Diseases are such that even if you have eliminated them, you have to keep working at prevention or they will resurge.”

Soil-Transmitted Helminthiasis

Building on the success of soil-transmitted helminth control - The future of deworming

Peter Mark Jourdan, Antonio Montresor and Judd L. Walson
PLoS Neglected Tropical Diseases
The global STH community is at a crossroads. Sustaining the incredible gains achieved by STH and LF programs will be challenging, particularly as STH prevalence and morbidity continue to decline and focus shifts to other competing global health priorities. The WHO and partners will need to continue to review the current STH strategy focused on morbidity control to ensure that STH-driven programs align with the evolving needs of STH-endemic countries, including assessing who should be treated, how frequently and the role of WASH in STH programs.

Meet the amazing cast behind a life-changing drug

PATH Blog
Worldwide, hookworm and other parasitic worms (what scientists call soil-transmitted helminths, or STHs) cause considerable harm. They’re a scourge on the world’s poorest communities—undermining nutrition, stunting growth, and increasing vulnerability to other diseases. And they affect a staggering 1.5 billion people...An underutilized drug called tribendimidine (TrBD) offers hope. Discovered by Chinese scientists from NIPD and approved by the China Food and Drug Administration more than a decade ago, TrBD is a safe and effective treatment for STHs. But to help more people, it still must earn approval from the FDA and prequalification from the World Health Organization. Completion of both steps could unlock global access of TrBD for use in MDA campaigns.

Trachoma

Progress and projections in the program to eliminate trachoma

Paul M. Emerson, Pamela J. Hooper and Virginia Sarah
PLoS Neglected Tropical Diseases
The global program has made tremendous progress. We have come further than we could possibly have hoped at the launch in 1998; but as strong as the global program is, we are also fragile. Any significant change in philanthropic philosophy, power, and politics can trump public health gains. The global program remains dependent on strong political will to succeed in endemic countries, the active participation of over 200 million people at risk, an unfaltering supply of donated medicine, a continuous pipeline of donor funds, increasing support to operational and basic science research, and access to all endemic areas. Despite the challenges, it is possible to eliminate trachoma as a public health problem. The world deserves our continued efforts and best work now so that future generations will never know the pain and suffering of trachoma.

Cross-cutting

Integrating neglected tropical diseases in global health and development: Fourth WHO report on neglected tropical diseases

Department of Control of Neglected Tropical Diseases
World Health Organization
This fourth WHO report on neglected tropical diseases (NTDs) reviews the progress made towards achieving the Roadmap targets for 2020, noting the remaining challenges, then looks beyond 2020 to evaluate the changing global health and development landscape, considering the implications of integrating these diseases into the broader 2030 Agenda for Sustainable Development.

A legacy of progress against Neglected Tropical Diseases

Thoko Elphick-Pooley
The Huffington Post
“The London Declaration on Neglected Tropical Diseases” has been instrumental in driving the tremendous gains made in the last five years. According to a new WHO fourth report on NTDs, nearly a billion people received NTD treatments in 2015; the number of people at risk of NTDs fell by 20 percent over the past five years; and, over 10 billion tablets, equivalent to over 7 billion treatments were donated by industry between 2012 and 2016.

Winning the war against ancient diseases

Susan Scutti
CNN
The World Health Organization is on track to meet its goals to control, eliminate or eradicate sleeping sickness, Chagas and other ancient illnesses by 2020...In 2007, a group of global partners convened by the WHO, agreed to tackle neglected tropical diseases together. A year later, the WHO published its Global Plan to Combat Neglected Tropical Diseases. Around the same time, the London Declaration on Neglected Tropical Diseases assembled partner organizations to try to help achieve these goals. "That combination has been extremely powerful and constructive," said Dr. Julie Jacobson, an expert in the field and a representative of the American Society of Tropical Medicine & Hygiene. Looking at the data before and after the WHO published its first plan in 2008, global achievements in reducing neglected diseases went from "pretty stagnant" to "increasing, sequentially, every year, the number of people that have been reached and countries that have achieved their targets," said Jacobson.

Drastic Reduction in Neglected Tropical Diseases During the Past 5 Years

Maria Rebollo Polo and C. Boakey-Agyemang
World Health Organization Regional Office for Africa
"Neglected Tropical Diseases (NTD) programmes harness diverse partnerships to drive impact - including across sectors, and countries. With communities and entire nations struggling under the burden of these diseases, increased financial support, stronger political commitment and better tools to prevent, diagnose and treat the diseases are vital to defeat NTDs. The window of opportunity to achieve the 2020 targets is right in front of us, and we cannot let it close. The success so far shows what can be done if we work together," said Dr Matshidiso Moeti.

Gates backs Big Pharma push to wipe out tropical diseases

Stephanie Nebehay
Reuters
The Bill and Melinda Gates Foundation, Western countries and drug companies pledged fresh support on Wednesday to wipe out diseases that blind, disable and disfigure millions of poor in tropical areas each year and urged new donors to join the fight..."The best thing with these diseases is not to debate whether they are neglected or not, but to proceed to make them history," Bill Gates told a global partners' meeting held at WHO.

Global coalition chips away at neglected tropical diseases

Amy Maxmen
Nature News
Gates told Nature that recent successes are the result of global partnerships between governments, companies and nongovernmental organizations that have formed over the past decade. Multiple groups, including the Gates Foundation, the US Agency for International Development (USAID) and the DFID, signed a global agreement in 2012 called the London Declaration on Neglected Tropical Diseases to eliminate or reduce the prevalence of ten neglected diseases by 2020.

A global attack on long-neglected tropical diseases is succeeding

The Economist
Critics of foreign aid often charge that it weakens the countries that receive it, by undermining their economies and governance. But support for tackling NTDs, and other health problems, has shown quite the opposite effect. It removes an obstacle that stops abjectly poor people bettering themselves. And, like efforts to control malaria, tuberculosis and HIV/AIDS, it improves public-health systems and disease surveillance. As countries become more organised they can often combine their programmes.

'Phenomenal' progress in fighting tropical diseases

Jane Dreaper
BBC News
In 2015, one billion people worldwide were treated for at least one tropical disease. Companies have donated seven billion treatments since 2012. The World Health Organisation said improving water and sanitation was key to driving further progress.

Closer than Ever

Stephanie Bialek
Our Global Voices
Today, hundreds of millions fewer people are suffering from NTDs, and several countries have eliminated them entirely. The achievements are impressive and worth highlighting: In the last five years, the number of people at risk for NTDs has been reduced by 20 percent—from 2 billion to 1.6 billion. River blindness has been eliminated in most of the countries in the Americas, with Guatemala (2016), Mexico (2015), Ecuador (2014), and Colombia (2013) declared “onchocerciasis-free.” In 2016, Morocco joined Oman in being verified as eliminating blinding trachoma as a public health problem. China, the Gambia, Ghana, Iran, Laos, and Myanmar have also reported reaching elimination targets. Guinea worm disease, which 30 years ago afflicted more than 3 million people in 20 countries, is on the brink of eradication, with just 25 cases in 3 countries last year.

Unprecedented progress against neglected tropical diseases reported

Pan American Health Organization
“The countries in our Region are close to eliminating some of the neglected tropical diseases with the help of partners and the finest technical cooperation led by PAHO and WHO, but we need more help to finish the job and rid the Americas of these tropical diseases that can be eliminated,” said Dr. Marcos Espinal, who heads Communicable Diseases and Health Analysis at the Pan American Health Organization (PAHO).

[VIDEO] The Power of Partnerships: An interview with Dr. Gautam Biswas, World Health Organization

International Trachoma Initiative
YouTube
Partnerships are critical to fighting trachoma, the world's leading infectious cause of blindness. We spoke to our partners about their experiences with partnerships to #endtrachoma and #beatntds.

Recognising the role of community-directed treatment and of women in the fight against NTDs

Uche Amazigo, Andy Crump and Tore Godal
The Lancet Global Health
In 2016, Bill Gates declared “the best leaders have the ability to do both the urgent things that demand attention today and, at the same time, lay the groundwork for innovation that will pay dividends for decades”. True agents of change, institutional or individual, should rightfully receive due recognition. TDR received the 2011 Gates Award for Global Health and ivermectin attracted a Nobel Prize in 2015. It is fitting that the immeasurably positive impact of women in accomplishing hitherto unimaginable advances in the health and wellbeing of resource-poor, remote populations is now being recognised too.

Neglected tropical diseases: A DFID perspective

Charlotte Watts
PLoS Neglected Tropical Diseases
Looking forward, we need to look for opportunities to achieve synergies in programming. The seven preventive chemotherapy diseases (ascariasis, hookworm infections, lymphatic filariasis, onchocerciasis, schistosomiasis, trichuriasis, and trachoma) are preventable by a simple oral drug treatment, administered once or twice a year. Due to the geographic overlap of endemic areas for some NTDs, and a common requirement for preventive chemotherapy, an integrated approach to mass drug administration has been increasingly adopted. This integrated approach provides a means to make cost savings and increase efficiency compared to single disease approaches.

Swiss TPH joins the Swiss Alliance against Neglected Tropical Diseases

Peter Steinmann
Swiss Tropical and Public Health Institute
Swiss TPH is a founding member of the “Swiss Alliance against Neglected Tropical Diseases (NTDs)". The Alliance was officially established on 20th of April 2017 on the occasion of the NTD Summit in Geneva with the aim of fostering collaboration and promoting innovation to address NTDs. The Alliance also aims to raise awareness for NTDs in Switzerland.

Other

Ugandans win prestigious awards

New Vision
Edridah Muheki Tukahebwa from Bulindo, Kampala and Grace Aciro Oyat from Abera, Lamwo, were unveiled as the big winners at last night’s Women in Focus Awards – a prestigious international initiative celebrating the crucial role women play in the ongoing fight against Neglected Tropical Diseases. Aciro, 45, beat off stiff competition from females around the world to scoop the coveted Women in Focus Inspirational Award, while fellow Ugandan Tukahebwa, 51, was awarded the Women in Focus Leadership Award (in honour of Likezo Mubila).

Belgium announces decisive push to eliminate sleeping sickness by 2025

Alexander De Croo
Minister De Croo announced in Geneva that Belgium will allocate 25,3 million euro (27 million US dollars) over the next nine years to eliminate sleeping sickness. In addition, the Bill & Melinda Gates Foundation has committed to match Belgium’s contribution to the fight against sleeping sickness. At the Second Global Partners’ Meeting on Neglected Tropical Diseases in Geneva, Belgium is also formally joining the international coalition to control, eliminate and eradicate 10 NTDs.

India eliminated kala azar in over 80 pc sub-districts in

Daily News & Analysis
India eliminated visceral leishmaniasis, also known as kala azar, in over 80 per cent of its sub-districts in 2015, the WHO today said while noting that remarkable achievements have been made by nations in tackling neglected tropical diseases (NTDs) since 2007..."In 2015, the target for the elimination of visceral leishmaniasis was achieved in 82 per cent of sub-districts in India, in 97 per cent of sub-districts in Bangladesh, and in 100 per cent of districts in Nepal," WHO in its new report 'Integrating Neglected Tropical Diseases in Global Health and Development' said.

Using Rapid Diagnostic Tests for Yaws and Syphilis in remote clinics in East Malaita – what do health workers think?

Tommy Esau
Atoifi Health Research Group
Most clinics visited described the [rapid diagnostic tests, or] RDTs for Yaws and Syphilis as being a very useful test for remote clinics where health facilities are limited. A health worker from Nafinua stated that “the test is cost- effective compared to what we have experienced before; where you have to wait for a long time, and usually takes a long process before result can be available. But this one as soon as you do the test result is available.”

Fighting Rabies With Awareness In The Philippines

Louise Taylor
The Huffington Post
The vital role of increasing awareness around rabies control is often overlooked, but not in the Philippines. For 18 years, even before the establishment of the National Rabies Act of 2007, the Philippines government has been declaring March “Rabies Awareness Month”. This month, a time chosen to help people understand the risks ahead of the school summer holidays, is used to remind everyone of the risk that unfortunately still causes between 200 and 250 Filipinos a year to die from this cruel, yet totally preventable disease.

Zika

Transmission of Zika virus through breast milk and other breastfeeding-related bodily-fluids: A systematic review

Susannah Colt et al.
PLoS Neglected Tropical Diseases
We describe three cases of ZIKV-infected breastfeeding mothers who were symptomatic within three days of delivery, and two cases with ZIKV-infected newborns. While ZIKV was detected in the breast milk of all three mothers, the data are not sufficient to conclude ZIKV transmission via breastfeeding. More evidence is needed to distinguish breastfeeding transmission from other perinatal transmission routes.

Zika mosquito is spreading worldwide but WHO wants to stop it

Andy Coghlan
New Scientist
Mosquitoes beware. The World Health Organization is preparing a global “vector control” plan to track the movements of disease-spreading organisms worldwide. “The idea is to prevent outbreaks of disease instead of simply reacting to new ones,” says Raman Velayudhan, head of vector control for neglected tropical diseases at the WHO.

Florida tests bacteria-infected mosquitoes to kill off Zika and other viruses

Associated Press
Thousands of bacteria-infected mosquitoes were released in the wild Tuesday near Key West, testing a new way to kill mosquitoes that carry Zika and other viruses. The Florida Keys Mosquito Control District released 20,000 male mosquitoes infected by the Kentucky-based company MosquitoMate with naturally occurring Wolbachia bacteria.

Zika fears return with warm weather

Tom Howell Jr.
The Washington Times
Rising U.S. temperatures are forcing federal and state officials to gird for yet another bout with Zika, the mosquito-borne disease that triggered unprecedented travel warnings to pregnant women and sent sales of bug-repellent soaring before fading from view over the winter. After dire warnings from some quarters last year, the Centers for Disease Control and Prevention says it won’t try to guess how many cases the U.S. will see this year, though the agency says “small pockets of transmission” similar to the flare-ups in Florida and Texas last year are likely.

‘They’re just hiding’: Experts say Puerto Rico may be underreporting Zika-affected births

Helen Branswell
STAT
The number of babies born in Puerto Rico with microcephaly and other birth defects caused by the Zika virus appears to be unexpectedly low — so low that experts are beginning to question whether the actual count is being significantly underreported by authorities on the island.

2 cases of Zika confirmed at Glasgow Road in Kovan

Channel News Asia
SINGAPORE: Two cases of locally transmitted Zika virus infection have been confirmed at the Glasgow Road area near Kovan, the National Environment Agency (NEA) said on Thursday (Apr 20). Both cases are residents in the area, it added.

Upcoming Events

NTD Summit 2017
April 19-22, Geneva, Switzerland
Uniting to Combat Neglected Tropical Diseases
2017 marks the 5th anniversary of the World Health Organization's roadmap on NTDs and the London Declaration. To celebrate this milestone, Uniting to Combat NTDs, the World Health Organization and the NTD community are hosting the NTD Summit in Geneva, Switzerland in April 2017.

Alan J. Magill Malaria Eradication Symposium
April 24, Washington, DC
Center for Strategic & International Studies
The gathering honors the life of the late Dr. Alan J. Magill, who inspired us with his vision of the achievable defeat of malaria.  Alan was former president of ASTMH, director of the malaria program at the Bill & Melinda Gates Foundation and program manager at the Defense Advanced Research Projects Agency (DARPA). The symposium will consist of three panels: progress towards malaria eradication and the critical role of the U.S., innovative science in support of elimination and countering resistance, and the role of the private sector, including faith based organizations, in malaria elimination. 

Global Challenges in Infectious Disease: Showcasing Social Science in Edinburgh
April 24, Edinburgh, Scotland
Edinburgh Infectious Diseases
This one day symposium has been organised by the Edinburgh Centre for Medical Anthropology and Edinburgh Infectious Diseases to bring together a wide spectrum of expertise in social sciences with relevance to infectious diseases research. 

2017 FETP International Nights 
April 25 & 26, Atlanta, Georgia (and via webcast)
TEPHINET Learning
The 2017 FETP International Nights will be held during the 66th Annual EIS Conference in Atlanta, Georgia, USA. This event, co-sponsored by TEPHINET and the CDC, gives FETP trainees from around the world the chance to present their work to a global audience of public health practitioners.

27th Annual Molecular Parasitology & Vector Biology Symposium
April 27, Athens, Georgia
Center for Tropical & Emerging Global Diseases
This year's Keynote Address will be by Dr. Rick Fairhurst from the NIAID Malaria Pathogenesis and Human Immunity Unit. This symposium provides an opportunity for participants in the parasitology and vector biology programs at the University of Georgia and other regional institutions to gather for a 1-day interactive conference on parasites and host/parasite interactions.

2017 Dana Center for Preventive Ophthalmology Meeting
May 6, Baltimore, MD
Bloomberg School of Public Health
The Dana Center for Preventive Ophthalmology at the Johns Hopkins Wilmer Eye Institute is pleased to announce this invitation-only event, which will feature world-renowned experts and Dana Center alumni discussing the most pressing public health issues in eye care today. Among the discussions will be: What are the next steps in public health ophthalmology, with particular focus on trachoma, cataract and low vision.

World Health Summit Regional Meeting - North America
May 8-9, Montréal, Québec, Canada
Université de Montréal + Institut de recherches Cliniques de Montréal
The world leaders in global health will be attending this prestigious event, including over 800 researchers, doctors, industry leaders, decision-makers, government members and civil society actors from around the world. Based on the theme of “Health and Healthcare Delivery in Pluralistic Societies,” this interdisciplinary event will focus on the question of human diversity in the practice, education, research and public policy pertaining to health.

ISNTD d3
May 16-17, London, UK
The International Society for Neglected Tropical Diseases
ISNTD d3 will bring together experts from within drug discovery and clinical trials to drive the debate and foster new partnerships & alliances leading to tangible outcomes in terms of new therapies to combat these diseases.

WorldLeish-6 Congress
May 16-20, Toledo, Spain
WHO ColIaborating Centre for Leishmaniasis
The Scientific Programme of the upcoming Congress will address issues ranging from molecules to disease control, with the patient as the main focus. The agenda will feature contemporary lectures, hot-topic sessions, and satellite symposia covering the latest developments on leishmaniasis. The educational programme of the Congress will strike a balance between the needs of basic research and clinical issues.

Vector Borne Disease 5 Day Workshop
May 22-26, Dubai, United Arab Emirates
The MENTOR Initiative
The MENTOR Initiative is now delighted to be able to offer a new training course designed specifically to strengthen the capacity of agencies to implement effective and coordinated vector borne disease control activities, either as a focus or as part of broader disease control activities.

Designing & Managing Public Health Information Systems
May 23-July 18, Online Course
PHII Informatics Academy
Designing and Managing Public Health Information Systems: 8 Steps to Success is a short, instructor-supported, distance learning course in public health informatics. Volume discounts apply for team registrations!

Antimicrobials and Drug Resistance
May 30-June 1, Las Vegas, USA
Antifungal and antiparasitic are class of medication for pharmaceutical fungicide or fungistatic used to treat and prevent mycoses and treatment of parasitic diseases, such as those caused by helminths etc, respectively. Invasive fungal infections causes significant health problem in immune compromised patients.  So as the clinical manifestations vary and can range from colonization in allergic broncho pulmonary disease to active infection in local aetiologic agents. Therefore drug dose monitoring is necessary to ensure the therapeutic levels achieved for optimal clinical efficacy.

Management and Leadership Course for Health Workers
June 5-9, Ibadan, Nigeria
West African College of Physicians
The West African College of Physicians (WACP) with the Faculty of Community Health and the Department of Health Policy and Management at University College Hospital & College of University of Ibadan announce the Management and Leadership Course for Health Workers. Our highly respected trainers are humbly urged to encourage their trainees to attend this course.

Health Systems Summer Institute
June 12-23, Baltimore, Maryland
Johns Hopkins Bloomberg School of Public Health
The new Health Systems Summer Institute provides early- and mid-career public health professionals the skills necessary to address key health systems issues of today. The Institute is also a great opportunity for part-time MPH and other Hopkins students and fellows to learn a valuable set of skills in an in-demand, and rapidly growing field of public health.

European Educational Programme in Epidemiology (EEPE)
June 13-July 7, Florence, Italy
International Epidemiological Association
The course is intended for epidemiologists, statisticians, clinicians and public health practitioners with an interest in epidemiology. The course is taught in English and held in residential form in the “Studium” centre, Florence.

Update Course in Clinical Tropical Medicine and Travelers' Health
June 14-15, Toronto, Ontario, Canada
American Society of Tropical Medicine and Hygiene
ASTMH has developed this course as an update in the essential components of tropical medicine and travelers' health. This two-day meeting is designed for physicians and for all other health care providers working in tropical medicine or travelers' health. Speakers are internationally recognized authorities in the field. 

The 7th International Lymphoedema Framework Conference
June 21-24, Siracusa, Sicily, Italy
The ILF 2017 Conference will gather practioners, researchers, affiliates and stakeholders from all over the world. It is thus a great opportunity to present your knowledge to a multi-stakeholder audience.

Global Health Focus: Repurposing for Rare Diseases and Orphan Drug Development
June 27-28, 2017
The 6th Annual Drug Repositioning, Repurposing and Rescue Conference
Featured Presentation: Lead Repurposing as an Effective Approach for Neglected Tropical Disease Drug Discovery

European Congress of Epidemiology
July 4-6, Lyon, France
International Epidemiological Association
The European Congress of Epidemiology 2018, titled Crises, Epidemiological transitions and the role of epidemiologists, will take place on July 4-6 2018 in Lyon, France.

Annual General Scientific Meeting
July 17-21, Asaba, Nigeria
West African College of Physicians
THEME:Universal Access to Health; A Basic Necessity for Attainment of the SDGs; SUB-THEME: Building Sustainable Health Care Leadership for SDG Goal 3; CONFERENCE WORKSHOP TOPIC: Quality of Health Care

Advanced Residential Course on Poverty-Related and Neglected Tropical Diseases
July 17-August 4, Pemba Island, Zanzibar
Ivo de Carneri
The Course is addressed to professionals active or interested in public health, with diverse cultural and scientific background and competence. The Course is a practical opportunity to acquire a solid knowledge and a critical understanding on PR&NTD, thanks to the expertise of a high quality teaching team made of African and European lecturers with firsthand experience in the domain.

IEA 2017 World Congress of Epidemiology
August 19-22, Saitama, Japan
International Epidemiological Association
Following the 20th WCE in Anchorage in 2014, we believe to provide opportunities to exchange information about the development of epidemiology in all the fields and to strengthen the relationship among epidemiologists in the world. The main theme is “Global/Regional/Local Health and Epidemiology in a Changing World”, which is appropriate one for discussing the 3-year development of epidemiology from 2014 through 2017.

International Workshop on Disease Mapping in Low-resource Settings
September 14-15, Lancashire, England
Lancaster University
Hosted by Lancaster University on 14 - 15 September 2017, the multidisciplinary workshop will bring together international statistics and epidemiology experts to discuss the mapping of a wide range of diseases including neglected tropical diseases and malaria. 

NNN Conference 2017
September 28-30, Dakar, Senegal
Neglected Tropical Disease NGO Network
NNN hosts its 2017 annual conference in Dakar, Senegal. More information to follow.

ASTMH 66th Annual Meeting
November 5-9, Baltimore, Maryland
American Society of Tropical Medicine and Hygiene
The ASTMH Annual Meeting draws tropical medicine and global health professionals representing academia, government, non-profits, philanthropy, NGOs, industry, military and private practice. The meeting is designed for researchers, professors, government and public health officials, military personnel, travel clinic physicians, practicing physicians in tropical medicine, students and all health care providers working in the fields of tropical medicine, hygiene and global health. 

Swedish-Ethiopian Course in Tropical Infections
November 13, 2017 - February 11, 2018, Stockholm, Sweden
Karolinska University Hospital
This is a course in clinical tropical medicine and HIV for clinicians. The overall aim is to provide general knowledge about infectious diseases which require or thrive in a warm climate and / or are important causes of morbidity and mortality in low-income countries. The focus is on diagnosis and treatment both in situations with scarce resources and in more affluent countries. The field visit to Ethiopia gives the participants a unique experience of the health system and infectious disease panorama in a developing country.

Eradicate Malaria World Congress 2018
February 18, 2018, Melbourne, Australia
The inaugural World Congress on Malaria - Eradicate Malaria 2018 - will bring together the broad global community including implementers, scientists, funders, governments, policy makers and those directly affected by the disease. The aim is to bring the broad spectrum of the malaria world together for the first time, to further galvanise the effort for the eradication of malaria.