Monitoring
Impact of Malaria Vector Control & Status of Lymphatic Filariasis Transmission in the Lake Zone of Tanzania
To assess filarial exposure in the study population and mosquito infection status prior to and after the start of intensified malaria control interventions.
Filariases Transmission Assessment Survey (F-TAS) in Burkina Faso
To study the feasibility of LF and Oncho (Filariases) integrated transmission assessment survey (F-TAS) according to both LF and Onchocerciasis WHO elimination guidelines
Understanding the best uses of the Supervisor's Coverage Tool (SCT) for monitoring school-based distributions
- To use the Supervisor's Coverage Tool (SCT) to monitor school-based deworming;
- To determine the feasibility of utilizing the Lot Quality Assurance Sampling (LQAS) methodology in a school-based SCT; and
- To apply a checklist in schools to elicit information about the performance of the MDA.
Laboratory analysis of Ov16 ELISA and Skin snip PCR to support surveillance activities in National programs. Multi-country comparison of diagnostic tools to detect Onchocerca volvulus.
To compare the performance of the diagnostic tools currently available for O. volvulus in terms of their relative sensitivity, species-specificity and practical use by countries. Comparison of the utility of these tools for mapping and surveillance in settings with different levels of endemicity for onchocerciasis (Oncho), lymphatic filariasis (LF) and/or loiasis.
Develop epidemiological and entomological methods to asses verification of transmission interruption of Onchocerciasis in Equatorial Guinea- Africa
After two decades of onchocerciasis control activities in Bioko island, transmission is expected to be interrupted. This study aims to demonstrate that WHO criteria to verify transmission interruption have been met. It also aims to standardize the reading of RDTs, particularly the FTS and Ov16, and reduce the potential for human error.
Single vs. multiple treatments of praziquantel in intestinal African schistosomiasis: a randomized, double-blind, placebo controlled trial investigation using new diagnostic tools
Rigorous assessment of the efficacy of (multiple) doses with Praziquantel in the treatment of S. mansoni infections using standard and novel highly sensitive diagnostic tools.
Understanding the best uses of the Supervisor's Coverage Tool for monitoring school-based distributions
To compare the feasibility and programmatic implications of employing the Supervisor's Coverage Tool in schools vs. communities to monitor a school-based MDA.
Supervisor's Coverage Tool for school-based STH and community-based LF in Philippines
To determine the feasibility and best practices of using the Supervisor's Coverage Tool to monitor community and school-based distribution and integrated MDA.
Relationships among clinical signs (Follicular Trachoma) and infection and antibody
The purpose of this study is to analyze the relationships among clinical signs (follicular trachoma) and the prevalence of infection and antibody and to determine whether it may be appropriate to consider one or more alternative indicators for deciding whether trachoma programs can stop MDA.
Community implementation and comparison of Human landing and Non human landing collection methods for vectors of Wuchereria bancrofti and Onchocerca volvulus for entomological monitoring of transmission (Ghana)
To determine the feasibility of the use of entomological traps by community members for onchocerciasis and lymphatic filariasis entomological assessments.